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2018Lecture 11 (2-12-18).pdf

2018Lecture 11 (2-12-18).pdf - Chapter 14 Energy Generation...

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Chapter 14 Energy Generation in Mitochondrion 1. Membrane-based Mechanism 2. Structure of Mitochondrion 3. Overview / Logic of electron transport 4. Electron Transport Chain 5. The Proton Gradient 6. The Proton-Motive Force 7. ATP synthesis - Four Multi-Protein Enzyme Complexes ( II not essential) - Complexes NOT fixed in membrane - Coupled Oxidation-Reduction reactions Figure 14-14 Complex I III IV Figure 14-14 Complex I III IV - NO short-circuit or skipping - Protons pumped (transferred) in each complex - one NADH = ~10 H + ; one FADH 2 = ~6 H + Chapter 14 Energy Generation in Mitochondrion 1. Membrane-based Mechanism 2. Structure of Mitochondrion 3. Overview / Logic of electron transport 4. Electron Transport Chain 5. The Proton Gradient 6. The Proton-Motive Force 7. ATP synthesis Proton-Motive Force = Force pushing protons DOWN the electrochemical Gradient Figure 14-15 Chemical concentration Electrical Potential Electron Transport Chain (Animation)
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Chapter 14 Energy Generation in Mitochondrion 1. Membrane-based Mechanism 2.
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