code.docx - 0 Gene control device Outer native RNA splicing...

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Unformatted text preview: 0 Gene control device Outer native RNA splicing - Cell can splice an RNA transcript diff erently and thereby make diff erent polypeptide chains f romthe same gene . Exarrple: budding yeast 0 Has 6,200 genes 0 300 slice - Occurs because an int ron sequence arrbiguity: stranded for removing intron sequence RNA editing . Alters the nucleotide sequences of transcripts once they are synthesized and thereby changes the coded message they carry 0 l n animals (2 types) 0 (Corrmon) deam'nation of adenine to produce inosine (A to I editing) 0 EX: ADARS 0 (less corrmon) deam'nation to cytosine to produce uracil (C to U editing) 0 Ex: apolipoprotein B Regulated nuclear transport . Mechanisms that deliberately override control point can be used to regulate gene expression - Occurs in Al DS virus, HIV Translation repressors - | nhibit translation initiation . Recognize nucleotide sequences in the 3'UTR of specifi c nRNA . Decrease translation initiation by interfering with comrunication between the 5’ cap and 3’ poly-A tail E|f2 - Binds to GDP, guanine nucleotide exchange factor require to cause GDP release so that a new GT P molecule can bind and elf 2 can be reused ...
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