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DQ2 Levels of EvidenceEvidence-Based Medicine (EBM) involves seeking evidence and using the evidence in making a clinical decision. Originally, the levels of evidence were illustrated in the periodic health report in 1979. The highest level of evidence describes were randomized clinical trials which are less likely to result in a systemic error due to the existence of randomization of confounding factors biasing the results. The report considered case series and expert opinion as for the lowest level of evidence due to their higher probability of being biased on the basis of author’s experience and lack of control of confounding factors (Groove & Cipher, 2016). The Center of Evidence-Based Medicine suggests that randomized clinical trialsare not essential in finding a disease prognosis thus considering cohort studies and systemic review of cohort studies as the highest levels of evidence. The levels of evidence of randomized clinical trials are asfollows;Level1A- systemic review of randomized clinical trials (RCT).