Chapter_32[1] - Chapter 32: Specific Immunity Recognizes...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 32: Specific Immunity Recognizes things as being non-self and produce a response to these foreign entities (antigens) Response has memory o Referred to as anamnestic response o 2 nd  exposure to same antigen   response is faster and more effective Response has specific to individual antigen Defense (2) o Humoral (antibody-mediated) o Cell-mediated immunity Terms Antigen: chemicals present on viral/bacterial surfaces that react w/ antibodies or lymphocytes o Immunogen: antigen that induces immune response Antibodies: glycoproteins that react  with antigen o Bind to antigenic determinant (epitope) = small region of antigen Haptens: not antigenic by themselves but are when combined w/ larger carrier protein Types of Acquired Immunity (4) Naturally acquired and active immunity o Host is expose to antigen and develop own antibodies vs pathogen o Host retain memory and can quickly produce more antibodies upon 2 nd  exposure o Ex: flu recovery with OTC drugs and immunity to that strain Naturally acquired and passive immunity o Host has pre-formed antibodies made by someone else o Host has no memory of antigen or antibody production of it’s own o Newborn’s immunity from mom’s IgA and IgG that works for 1 st  2 month of life Artificially acquired and active immunity o Host is vaccinated with attenuated or killed pathogen o Host make antibodies to this antigen and retain memory of antigen and antibodies vs it o Ex: measles vaccination Artificially acquired and passive immunity o Host given pre-formed antibodies vs pathogen via vaccination o Antibodies formed by other infected individuals o Host has no memory of antigen/antibody production of its own o Ex: Gamma globulin for immunocompromised patients Vaccinations(3) Living attenuated agents (modified): antigenic and can replicate, but modified to not cause disease under  normal circumstances Inactivated immunizing agent: killed bacterial/virus bacterial toxin that may contain whole agents or subunits Recombinant vaccines (genetically engineered): can have edible vaccines where antigens are put into food Antibodies: Characteristics
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Aka: immunoglobulin (Ig) Made of glycoprotein 5 human class: IgM (pentamer) IgG (dimer) IgA, IgD, IgE (monomers) Anatomy o Y-shaped: 2 heavy (H) and 2 light (L) chains  with own constant (Fc) and variable (Fv) regions
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/25/2009 for the course MIBO MIBO 3500 taught by Professor Dustman during the Spring '09 term at University of Georgia Athens.

Page1 / 8

Chapter_32[1] - Chapter 32: Specific Immunity Recognizes...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online