Lec 4 LS2 W09

Lec 4 LS2 W09 - Energy Enzymes and Metabolism Energy Energy...

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1 Energy, Enzymes, and Metabolism Energy • Energy is the capacity to do work, or the capacity to change • Energy transformations are linked to chemical transformations in cells • Energy can be transformed from one type to another – Potential and Kinetic energy Metabolism • Anabolic • Catabolic • First Law of Thermodynamics • Second Law of Thermodynamics
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2 Free energy of a reaction • Measure of potential energy • Gibbs stated that “all systems change in such a way that free energy is minimized” G = G products - G reactants Free Energy Δ G = Δ H – T Δ S If Δ G is negative, free energy is released. If Δ G is positive, free energy is consumed. If free energy is not available, the reaction does not occur.
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3 Where do some reactions get the energy to go up the hill? Reactions can be coupled
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4 ATP coupled reactions Enzymes • Terminology - name indicates its structure or function. • Ends in the suffix -ase, protease, ribonuclease • Enzymes are highly specific • Function by lowering the activation energy of the
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Lec 4 LS2 W09 - Energy Enzymes and Metabolism Energy Energy...

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