Lec 5 F09 - Which way do we go? 4 Another Overview Feedback...

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1 Cellular Respiration and Fermentation Metabolism - the reactions that occur within all living cells Food as Fuel The most common fuel used by organisms is glucose When glucose burns, energy is released as heat and light: C 6 H 12 O 6 + 6 O 2 6 CO 2 + 6 H 2 0 + 686 kcal/mol The same equation applies to the metabolism of glucose by cells, but the reaction is accomplished in many separate steps so that much (>50%) of the energy can be captured as ATP. The majority of this energy is released in oxidation-reduction (redox) reactions, with the energy initially captured by a molecule called NADH, and then the energy of NADH supplies the energy for production of ATP.
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2 Oxidation-reduction reactions OIL-RIG Are we really burning glucose? • Glucose doesn’t burn in cells • Glucose is oxidized through a series of reactions (redox reactions) • The change in free energy that occurs during the oxidation of glucose is used to create ATP
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3 Key Player
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Unformatted text preview: Which way do we go? 4 Another Overview Feedback inhibition 5 Pyruvate Processing 6 Where do these reactions occur? 7 How does glucose oxidation form ATP? Another Step down the Ladder 8 ATP Synthase 9 Overview Metabolic pathways are connected 10 What is produced form different steps? What happens when oxygen is not present? • Fermentation occurs when pyruvate or its derivative, rather than oxygen, accepts electrons from NADH. Fermentation converts NADH back to NAD + and allows glycolysis to continue to produce ATP via substrate-level phosphorylation. • In lactic acid fermentation , pyruvate produced by glycolysis accepts electrons from NADH. Lactate and NAD + are produced. • In alcohol fermentation , pyruvate is enzymatically converted to acetaldehyde and CO 2 . Acetaldehyde accepts electrons from NADH. Ethanol and NAD + are produced. 11 Fermentation...
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This note was uploaded on 04/26/2009 for the course LIFESCI 2 taught by Professor Pires during the Winter '08 term at UCLA.

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Lec 5 F09 - Which way do we go? 4 Another Overview Feedback...

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