2-18-09 - 2-18-09Effects of selection on gene fregquencies...

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Unformatted text preview: 2-18-09Effects of selection on gene fregquencies in mendelian Traitsselection against the dominant alleleothe concept of fitnessis relativeis the rate of increase (r),or Reproductive successof one pheontype in a population relative toother phenotypescan be measured and modeled mathematicallyin models W is the symbol used to identify the fitness of best adapted phenotypeW = 1For all other phenotypes, fitness MUST be less than 1Achondroplasia: disproportionate dwarfismoA point mutation: locus on chromosome #4oDefect of cartilage & bone formationoRate = 1/240,000 births (to non-afflicted parents)oMost cases are the result of mutationoHeterozygotes have he traitoSelection against DD phenotype through mortality differential: all homozygotes DIEoHeterozygotes live but have the trait. But what about their FITNESS?Selection against the Dd phenotype through fertility defferentialoSelection against dominantDominant allel selected against in the two phenotypes produced by AA, Aa, and aA genotypes...
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This note was uploaded on 04/27/2009 for the course ANTHRO 304 taught by Professor Gray during the Spring '09 term at Kansas.

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2-18-09 - 2-18-09Effects of selection on gene fregquencies...

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