Quiz 6 key

Quiz 6 key - 1 Quiz 6 Key Biology 340 General Genetics...

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Quiz 6 Key, Biology 340, General Genetics, Spring, 2008 1. RNA interference – a) what is microRNA and, in general, what is one way that they are able to regulate gene expression? b) what is the role of Dicer with microRNA? a) MicroRNA are short RNA molecules that are encoded in an organisms genome. These molecules may interact with RISC and bind to a mRNA molecule which is then cut by Slicer. Or the microRNA may bind to the 3’UTR of the mRNA and in an unspecified way cause the poly A tail to be deadenylated. Either way the mRNA that has been targeted by the microRNA will not be translated. b) Dicer modifies the initial microRNA transcript to produce a functional microRNA. 2. The following mutation occurred in the coding region of a gene: GCG to GAG. a) is this a transition or a transversion? Please explain. b) what is the general term for this type of mutation at the level of DNA? c) is this mutation a missense mutation or not? How could you know this without a copy of the genetic code? GCG to GAG a) this is a transversion.
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This note was uploaded on 04/27/2009 for the course BIO 340 taught by Professor Steele during the Spring '09 term at Arizona.

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Quiz 6 key - 1 Quiz 6 Key Biology 340 General Genetics...

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