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quiz2d - on the dose prescribed However Drug D also results...

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Name_________________________ Quiz 2d – Apopka The following questions refer to the log-dose-response curve shown below. Decide whether each statement is TRUE (A) or FALSE (B) (1 pt each) 1. Drug A is a less efficacious agonist than Drug C. 2. Drug B is a less efficacious agonist than Drug C. 3. Drug B is a less efficacious agonist than Drug A. 4. Drug C is a less potent agonist than Drug A. 5. Drug B is a less potent agonist than Drug A 6. Drug C is a less potent agonist than Drug B. 7. Curve C has a shallower slope than Curve B. 8. Curve A has a shallower slope than Curve C 9. Curve B has a shallower slope than Curve A 0 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration % Maximal response A B C
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Name_________________________ Drug D, taken every day for 6 months, results in a weight loss of 5 KG or more in most people depending
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Unformatted text preview: on the dose prescribed. However, Drug D also results in irreversible primary pulmonary hypertension in a significant number of people, again depending on the dose taken. (2 pts each) Weight Loss Hypertension ED1 .3 TD1 3 ED50 30 TD50 300 ED99 3000 TD99 30000 Which of the following statements are true (A) and which are false (B)? 10. The therapeutic index for Drug D is 10. 11. The certain safety factor for Drug D is 3 divided by 30. 12. Drug D should be taken off the market. 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration Cumulative % responding Hypertension Weight loss...
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