Micro Test 4 Name Summary

Micro Test 4 Name Summary - 1 Influenza a Drugs i...

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1. Influenza a. Drugs i. Prevention 1. Tamiflu (oseltamivir) 2. Flumadine (rimantadine) 3. Symmetrel (Amantadine) ii. After contraction 1. Amantadine 2. Rimantadine 3. Zanamivir 2. Picornaviruses a. (+) ssRNA b. Naked virus is infectious 3. Poliovirus a. Replicates in the brain b. Drooping of foot is a sign of polio c. Post-polio syndrome i. Muscular weakness and paralysis many years later 4. Viral Meningitis a. More common than bacterial b. Clear cerebral spinal fluid c. Coughing, sneezing poor hygiene d. Severe cases produce neurological defects 5. Enteroviruses a. Poliovirus, Coxsackie A and B, ECHO b. Stable at pH 3 6. Hepatitis Types A B C D E Source Feces Blood/blood derived body fluids Blood/blood derived body fluids Blood/blood derived body fluids Feces Route Fecal-oral Percutaneous permucosal Percutaneous permucosal Percutaneous permucosal Fecal- oral Chronic Infection No Yes Yes Yes No Prevention Pre/post exposure immunization Pre/post exposure immunization Blood donor screening; risk behavior modification Pre/post exposure immunization; risk behavior modification Ensure safe drinking water
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Hepatitis B a. ds and ss DNA together b. Liver cancer c. Reverse transcriptase, DNA polymerase and RNase H found in virus d. DNA=> cccDNA => pregenome RNA => RNA/DNA=> ssDNA/dsDNA e. Stuff i. Clinical illness (jaundice) 5+years 30-50% ii. Chronic infection <5 years 30-90% f. 41% heterosexually transferred 8. Hepatitis C a. Flavivirdae family b. (+) ssRNA genome c. Chronic liver disease and cancer d. 40-60% of chronic liver disease related with HCV e. Stuff i. Chronic infection 75-85% ii. Chronic hepatitis 70% iii. Cirrhosis 10-20% f. Injection drug use 60% of cases g. Most people with hemophilia Hepatitis C 9. Ribavirin a. Drug treatment for hepatitis C b. Activity i. Inhibits nucleoside biosynthesis ii. Inhibits capping of mRNA iii. Inhibits RNA polymerases 10. Herpesvirus a. Neurotrophic i. Varicella-Zoster virus b. Salivary gland tropic i. Cytomegalovirus c. Lymphotropic i. Epstein-Barr virus d. Structure i. Linear dsDNA ii. Enveloped iii. Naked is infectious e. Multiplication cycle i. Attachment ii. Penetration iii.
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Micro Test 4 Name Summary - 1 Influenza a Drugs i...

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