quiz2a - single dose. However, a higher dose, taken one...

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Name_________________________ Quiz 2a – St. Pete The following questions refer to the log-dose-response curve shown below. Decide whether each statement is TRUE (A) or FALSE (B) (1 pt each) 1. Drug B is a less efficacious agonist than Drug A. 2. Drug B is a less efficacious agonist than Drug C. 3. Drug A is a less efficacious agonist than Drug C. 4. Drug B is a less potent agonist than Drug A. 5. Drug A is a less potent agonist than Drug C 6. Drug C is a less potent agonist than Drug B. 7. Curve C has a shallower slope than Curve B. 8. Curve A has a shallower slope than Curve C 9. Curve A has a shallower slope than Curve B 0 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration % Maximal response A B C
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Name_________________________ Drug A provides significant relief from moderate pain, such as tension headaches, in most patients after a
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Unformatted text preview: single dose. However, a higher dose, taken one time, is also capable of causing significant irreversible hepatotoxicity 48 hours later in most people. (2 pts each) Headache relief Hepatotoxicity ED1 .003 TD1 1 ED50 0.3 TD50 100 ED99 30 TD99 10000 Which of the following statements are true (A) and which are false (B)? 10. The therapeutic index for Drug A is 100 divided by 0.3. 11. The certain safety factor for Drug A is 1 divided by 30. 12. Drug A should be taken off the market. 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration Cumulative % responding Hepatotoxicity Headache relief...
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quiz2a - single dose. However, a higher dose, taken one...

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