quiz2b - Drug B provides significant relief from more...

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Name_________________________ Quiz 2b – Jax The following questions refer to the log-dose-response curve shown below. Decide whether each statement is TRUE (A) or FALSE (B) (1 pt each) 1. Drug B is a less efficacious agonist than Drug A. 2. Drug C is a less efficacious agonist than Drug A. 3. Drug C is a less efficacious agonist than Drug B. 4. Drug B is a less potent agonist than Drug A. 5. Drug C is a less potent agonist than Drug A 6. Drug C is a less potent agonist than Drug B. 7. Curve B has a shallower slope than Curve A. 8. Curve C has a shallower slope than Curve A 9. Curve C has a shallower slope than Curve B 0 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration % Maximal response A B C
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Unformatted text preview: Drug B provides significant relief from more severe pain, such as that occurring after major surgery, in most patients after a single dose. However, Drug B is also capable of causing significant nausea and vomiting in most people. (2 pts each) Analgesia Nausea ED1 1 TD1 3 ED50 100 TD50 300 ED99 10000 TD99 30000 Which of the following statements are true (A) and which are false (B)? 10. The therapeutic index for Drug B is 300 divided by 10. 11. The certain safety factor for Drug B is 3 divided by 1000. 12. Drug B should be taken off the market. 10 20 30 40 50 60 70 80 90 100 0.01 0.03 0.1 0.3 1 3 10 30 100 300 1000 3000 Drug concentration Cumulative % responding Nausea Analgesia...
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This note was uploaded on 04/27/2009 for the course CHM 2046 taught by Professor Veige/martin during the Spring '07 term at University of Florida.

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quiz2b - Drug B provides significant relief from more...

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