Sickled cells tangle block blood vessels tissue

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Unformatted text preview: ge protein 4 polypeptide chains (2 alpha, 2 beta) Each chain contains an iron containing heme group Iron binds O2 for transport Globin chains bind CO2 for transport Structure of Hemoglobin Figure 17.4 Leukocytes WBC = white blood cell 4000 11,000/L Nucleus 5 types: Neutrophils Eosinophils Basophils (Mast cells in tissue) Lymphocytes T and B (some B's are Plasma cells) Monocytes (Macrophage in tissue) Figure 24-4 Neutrophils Most abundant type (NLMEB Never Let Monkeys Eat Bananas) Phagocytic eat bacteria Release cytokines Pyrogens to increase body temperature (fever) Chemicals that cause inflammation Eosinophils Allergic reactions Release chemicals that contribute to inflammation and tissue damage Kill parasites (worms) Release chemicals to kill (cytotoxic cells) Basophils Inflammation + Allergic reactions Histamine vasodilation, bronchoconstriction Heparin inhibits blood clotting Other cytokines Mast cells in tissues of skin, lungs, digestive tract Monocytes Don't spend much time in blood Invade tissues Macrophages Macrophages: Very effective phagocytes Antigen-presenting cells fragments of processed antigens are displayed on cell surface for recognition by other cells to ultimately stimulate production o...
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This note was uploaded on 04/29/2009 for the course BIOL 425 taught by Professor Tondi during the Fall '08 term at George Mason.

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