Lec 4Chemical_Hazards_09 - Peanut Butter Outbreak Update...

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Peanut Butter Outbreak Update Peanut Butter Outbreak Update 108 people (22%) were hospitalized 8 deaths; all person > 59 years of age 50% of the cases occurred in children < 16 As of 1/28; 6:15 pm
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Peanut Butter Outbreak Update Peanut Butter Outbreak Update FDA inspection of plant started on 1/9 FDA inspection report on FDA web site; many GMP violations Internal records showed that Salmonella stains were found in finished product; tested by outside testing lab, found negative and shipped Recall now expanded to all products from the plant back to January 1, 2007 As of 1/28; 6:15 pm
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Factors Increasing the Risk of Factors Increasing the Risk of Foodborne Infection or the Foodborne Infection or the Severity of Illness Severity of Illness Pathogen Host Environmental
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Host Factors Host Factors Age less than 5 years * Lack of developed immune system * Smaller infective dose-by-weight Age greater than 50 or 60 years (depending on pathogen) * Immune systems failing; weakened by chronic illnesses Pregnancy * Altered immunity during pregnancy Hospitalized persons Morgan Dockter Died, Age 3 E. coli O157:H7
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Host Factors Host Factors Concomitant infections Consumption of antibiotics * Alteration of normal intestinal flora Excessive iron in blood * Serves as a nutrient for certain organisms Reduced liver/kidney function (alcoholism) * Reduced digestion capabilities
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Host Factors Host Factors Possession of certain human antigenic determinants duplicated or easily mimicked by microorganisms * Predisposition to chronic illnesses Surgical removal of portions of stomach or intestines * Reduction in normal defense systems
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Host Factors Host Factors Immunocompromised individuals… including those on chemotherapy or radiation therapy; recipients of organ transplants taking immunocompromising drugs; persons with leukemia, AIDS, or other illnesses Stress * Body metabolism changes Poor hygiene * Increased likelihood of ingestion of pathogens
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Persons with AIDS and Persons with AIDS and Late-Stage HIV Late-Stage HIV Salmonellosis * 20 times higher risk * 6 times more likely to develop life- threatening blood disease Listeriosis * 200-300 times higher risk * 25% of cases end in death
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Diet Related Factors Diet Related Factors Nutritional deficiencies… * either through poor absorption of food (mostly ill or elderly persons) * unavailability of adequate supply of food (starving persons) Consumption of antacids * Increase stomach pH Consumption of large volumes of liquids, including water * Dilution of stomach acids & rapid transit
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Diet Related Factors Diet Related Factors Ingestion of fatty foods (such as chocolate, cheese, hamburger) containing pathogens * Protection of pathogens by fat against stomach acids
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This note was uploaded on 05/05/2009 for the course FD SC 396 taught by Professor Gravani during the Spring '09 term at Cornell University (Engineering School).

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Lec 4Chemical_Hazards_09 - Peanut Butter Outbreak Update...

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