FST+160+Mar+4+Beyond+the+Bench

FST+160+Mar+4+Beyond+the+Bench - Be as close to real as...

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Beyond the Bench Production and Product Life Cycle FST 160 March 4, 2009
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Today… “Scale-up”, i.e., expanding the lab recipe for production Issues in scale-up Guidelines for scale-up Product Life Cycle
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Does the product meet the hurdles? Not necessarily in this order Consumer testing Marketing and sales goals Cost parameters Technically feasible
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Selected Prototype (Made on the bench) PT 1 PT 3 PT 2 PT … PT 4 Trial productions for Scale-Up (small scale) Pilot Plant Full scale Production Distribution Management Approval Test Market or Market Roll-out
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What is scale up? Aka Production Trials More than larger equipment Number of plants Modified or new equipment Manufacturing capabilities Location of plant(s) Environment Ingredient source Processing variables
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Processing variables Batch size Manual vs. automated conditions Batch vs. continuous process Transit or cycle time Packaging
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Work closely with Manufacturing, Engineering
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Unformatted text preview: Be as close to real as possible Batch size considerations Physical forces Surface area Time considerations Speed of manufacturing Rework WASTE By-products Water Air Energy Guidelines to Manage Scale-Up Gold Standard vs. Product Target Critical Control Limits Note differences in products at different stages Different manufacturing locations Suppliers: primary and secondary Economic factors Timing assumptions Unit Operations Consideration Or, manufacturing stagesconsider: Amount of product Availability of equipment Scale up equations for equipment From engineers, others Use to predict impact of changes Product Life Cycle How to end a product? May occur at any time but usually when sales decline Other reasons? Management decision Butmaybe they never die!...
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This note was uploaded on 05/03/2009 for the course FST 160 taught by Professor Giovanni during the Spring '08 term at UC Davis.

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FST+160+Mar+4+Beyond+the+Bench - Be as close to real as...

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