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QUIZ_9_Key.pdf - All of the foLLowing are consequences of...

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Unformatted text preview: All of the foLLowing are consequences of bare lymphocyte syndrome {MHC II deficiency] EXCEPT q. 1‘ the MHC II molecule is expressed on APB. - T cells will not form into TH1, THE, or other types of helper T cells. Cytotoxic T cells cannot be activated. B ceils do not isotype switch. Which of the following is true regarding T—ceLL deficiencies? ‘ '1" A mutation in the lL-E receptor affecE T-ceLL proliferation. ' A deficiency in ATP causes apoptosis in T, B, or NK cells ' lmmunoglobulin protection is permanent - Severe combined immunodeficiencies [SCIDs]: are characterized by a Laclt of B celE. All of the foLLowing are examples of B-cell disorders EKCEPT ' X-Llnlted agammagLobulinemia {Burton's disease]. co mm on variable immunodeficiency {Gilli}. qr * DiGeorge syndrome. selective lgA deficlency. Complement deficiencies are acquired during life. X—Linlted. qr * inherited autosomaltraits UEEII'EU With antivirals Leukeml'a refers to 1. '° a malignant Lymphoid cell found in circulation or bone marrow. a solid mass in a lymphoid organ. growth of a plasma celL cancerous plasma cells that appear at multiple sites All of the foLLowing are true about Hodgkin's lymphoma EXCEPT that 1' '9' it is often caused by the herpes slmplert vims. symptoms include fever, night sweaE, and weight loss. ' tumors contain neopLastic, multinucleated Reed-Sternberg celE. ' the release of cytoltines sum as TNF—alpha contributes to the fever and chronic inflammatlon. All of the following are true about B—cell neoplasms EXCEPT q. *' cancers arise in B cells when genes that control cell division are dysregulated and failto replicate. follicular lymphoma occurs when the bat—2 gene is activated and prevents apoptosis. ' chronic lymphocytic Leukemia occurs when there is a deletion in chromosome 13. Burkitt’s Lymphoma develops when the c—myo gene moves next to expressed antibody gena. All of the following are examples of antibody-mediated hypersensitivities ExCEPT hypersensitivity. lgE—mediated - antibody-mediated cytotoxic immune complex—mediated q: 1' cell-mediated Anophytoxis is the term for reactions caused when certain antigens combine with q * lgE antibodies. macrophages. lgG antibodies. hista mine. Epinephrine is used to reverse anaphylaxis. This is achieved by all of the following EXCEPT ' stimulating adenylate cyclase activity. in *' decreasing cAMP levels. relaxing smooth muscle. preventing degranulation of the mast cell. Which of the following blood transfusions would be compatible? ’ '°' A7AB+ AWO— ABU‘O— BWB' Symptoms of an immune complex reaction are due to destruction of the antigen. in 4! complement activation. phagocytosis. ' . - cytokines. Aliergic contact dem1 atitis is due to up * sensitized T ceLE. - lgE antibodies. lgG antibodies. - lgM antibodia. An autoimmune response is generated within the host when in *' immune tolerance against self is lost. immune cells attack foreign antigens NK cells bind host tissue. - T cells deactivate self—reacting B celis Which of the following is the major player in transplant rejection? in 1' MHC proteins of the donor T helper celE of the donor MHC proteins of the host T helper celE of the host Sensitivity differs from specificity in that sensitivity measura how selective an antibody is occurs when antibodies bind dissimilar antigens. in 4" reflecE how few antigen or antibody moLecuLes a test can detect. is not important when conducting a serological mt All of the foLLovving are examples of passive immunization EXCEPT injection of immune globulin. breast-feeding. antitoxins. qr 1" vaccinia virus. Determine the FAIjE statement below. An effective vaccine up 9 will deactivate B and T cells. will generate memory. should not require many boosters must protect against the natural pathogen. Ali of the foLLowing are generalbj used in 1«raccines EXCEPT toxoids. parts of bacterial cells. q: '1" antibodies. inactivated 1«riruses The foilowing are aLL true about herd imr'nunit'gl.r EXCEPT that it ' onLy wonrs for diseases that are contagious. - occurs when a Large portion of a popuLation is immunized. up 4" is possibLe for non-contagious infections Like tetanus ' protecE unirnmunized individuals. ...
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