2007 Final

2007 Final - NAME_ FINAL EXAM BICD100 GENETICS WINTER 2007...

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NAME________________________________ Page 1of 13 FINAL EXAM BICD100 GENETICS WINTER 2007 PROF. REINAGEL MARCH 21, 2007 8:00-11:00AM Name: Student ID: Exam Location: Sign here if you want your graded exam left in the hallway on the 3 rd Floor of Pacific Hall for you to pick up after Spring Break: Signature: QUESTION POINTS POSSIBLE POINTS EARNED 1 8 2 8 3 8 4 8 5 8 6 6 7 10 8 8 9 8 10 8 SUBTOTAL 80 extra credit 2
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NAME________________________________ Page 2of 13 Question 1. 8 points parts a - f In cats, the autosomal gene Tailless controls both tail length and viability. Cats with the wild-type TT genotype are viable with long tails. The t allele has a dominant phenotype of tailless (Tt = no tail), and also a recessive phenotype of lethality (tt = dead). Cross 1: You cross a tailless cat (Tt) with a wild-type (TT) cat. Cross 2: You select tailless cats a) Draw a Punnet Square diagramming Cross 1 b) Draw a Punnet Square diagramming Cross 2 from the F1 generation of Cross 1, and mate them to each other. (2pts) (2pts) c) What are the genotype(s ) of the F1 progeny from this cross, and in what ratio do they occur? (1pt) d) What are the phenotype(s) of the F1 progeny from this cross and in what ratio do they occur? (1pt) e) What are the genotype(s ) of the F2 progeny from this cross, and in what ratio do they occur? (1pt) f) What are the phenotype(s) of the F2 progeny from this cross and in what ratio do they occur? (1pt)
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NAME________________________________ Page 3of 13 Question 2. 8 points parts a, b, c In rabbits, the Mitten gene is X-linked. The wild-type M allele has a dominant phenotype of pigmented paws; the m allele has a recessive phenotype of “mittens” (white paws). The Giant gene is autosomal. The wild-type g allele has a recessive phenotype of normal size; the G allele has a dominant phenotype of large size (giant). You cross a normal sized female who also had the mittens phenotype, to a male from a pure-breeding strain of rabbits that have giant size and pigmented paws. a) Use a Punnet Square, tree diagram, or probability equation to completely diagram this cross. A complete answer must indicate the genotypes of both parents , the types of gametes produced by each of the parents, and the genotypes and phenotypes of the F1 progeny resulting from each possible gamete combination. (total 4 pts) b) Based on your answer to (a) what are the phenotypes among FEMALES in the F1 generation, and in what ratio do they occur? (2pts) c) Based on your answer to (a) what are the phenotypes among MALES in the F1 generation, and in what ratio do they occur? (2pts)
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NAME________________________________ Page 4of 13 Question 3. 8 points parts a, b, c Inspired by Luria-Delbruck’s Fluctuation Test, you decide to study the origin of mutations in yeast. You start with wild-type haploid yeast that are sensitive to an anti- yeast drug, and analyze the occurrence of novel, drug-resistant mutants.
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This note was uploaded on 05/04/2009 for the course BICD 660930 taught by Professor Reinagel during the Spring '09 term at UCSD.

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2007 Final - NAME_ FINAL EXAM BICD100 GENETICS WINTER 2007...

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