LEC 8 - MCB 102 Professor Buchanan 3/13/09 Lecture 22 ASUC...

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MCB 102 Professor Buchanan 3/13/09 Lecture 22 ASUC Lecture Notes Online is the only authorized note-taking service at UC Berkeley. Do not share, copy or illegally distribute (electronically or otherwise) these notes. Our student-run program depends on your individual subscription for its continued existence. These notes are copyrighted by the University of California and are for your personal use only. D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. ANNOUNCEMENTS I will be away a week from today, and there will be a guest lecture instead. I’m going to Japan for most of spring break, and so I will have to rearrange my office hours for the week of May 16. This will be posted on bSpace. Also, all the lectures up to today will be available on bSpace as well. LECTURE Last time, we ended with the catabolic fates of pyruvate. The pyruvate decarboxylation step is a unidirectional process and is irreversible. This is because the NADH that donates a hydrogen is too electropositive to reverse the reaction. In anaerobic cells, the reaction is reversible due to the ferredoxin molecule that receives the electron, transforming pyruvate into acetyl CoA. Ferredoxin and hydrogen are roughly at the same reduction potential. Table 13-7 shows the reduction potentials of many of the reactions, and you can see the ferredoxin reduction potential is the most negative of all of them. Citrate synthesis can also be reversal in certain cases, in which citrate yields the appropriate precursors. So it turns out that the citric acid
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MCB 102 ASUC Lecture Notes Online: Approved by the UC Board of Regents 3/13/09 D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. 2 cycle can actually be reversed in photosynthetic bacteria. Lecture 8: Fatty Acid Catabolism One relatively new phenomenon, particularly in the United States, is the problem of obesity. More and more people are becoming overweight. It just brings home the complexity and difficulty of the problem. So today, we’ll be talking about the structures
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LEC 8 - MCB 102 Professor Buchanan 3/13/09 Lecture 22 ASUC...

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