LEC 4 - MCB 102 Professor Buchanan 3/4/09 Lecture 18 ASUC...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
MCB 102 Professor Buchanan 3/4/09 Lecture 18 ASUC Lecture Notes Online is the only authorized note-taking service at UC Berkeley. Do not share, copy or illegally distribute (electronically or otherwise) these notes. Our student-run program depends on your individual subscription for its continued existence. These notes are copyrighted by the University of California and are for your personal use only. D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. LECTURE In lecture two, we talked about glyceraldehyde 3- phosphate dehydrogenase. As I said, the picture in the textbook was different from some other resources. I contacted someone else about this, and he assured me that either mechanism is correct at this stage. What may be incorrect is that the enzyme is equally reactive when NAD is bound to the Cys residue. Last time, we talked about the pentose phosphate pathway. We covered the oxidative phase, in which glucose 6-phosphate is oxidized to ribulose 5- phosphate with two equivalents of NADPH. This is required for the synthesis of fatty acids, sterols, etc. It can then be converted into ribose 5-phosphate, which is then used for nucleotides, DNA, and RNA. The nonoxidative phase is used to regenerate the glucose 6-phosphate at the beginning of the pathway. It is important to remember that glucose 6- phosphate is the beginning substrate for the pathway, which forms 6-phosphogluconate. 6- phosphogluconate regenerates o-ribulose phosphate.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
MCB 102 ASUC Lecture Notes Online: Approved by the UC Board of Regents 3/4/09 D O N O T C O P Y Sharing or copying these notes is illegal and could end note taking for this course. 2 The book also shows the nonoxidative reactions of the pentose phosphate pathway in figure 14-22. This regenerative phase of the nonoxidative reactions is rather involved, and you won’t be expected to know it for the exam. You can go ahead and do the arithmetic of the pathway yourself. When you study for the exam, all the questions should come exclusively from the lecture, unless I forgot what exactly I covered in lecture. It’s a lot of reading, but I think it is interesting reading, and it provides important background information. Lecture 4: Principles of Metabolic Regulation:
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 5

LEC 4 - MCB 102 Professor Buchanan 3/4/09 Lecture 18 ASUC...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online