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Unformatted text preview: acetylcholine esterase examples: curare, nerve poisons, botulinum toxin, tetanus toxin excitation-contraction coupling T-tubules and Ca channels/DHP receptors SR and ryanondine receptors (RyR-Ca channels), Ca release (regulate contraction - Tn) Ca uptake by SR Ca-ATPase (SERCA): Ca bound to calreticulin and calsequestrin Summary: nerve, NM junction, action potential, EC coupling, contract and relax Regulation twitch, summation, tetanus motor unit use and coordination isometric vs. isotonic vs. eccentric contractions muscle types slow twitch, oxidative, red, posture fast twitch, oxidative, red, walking and endurance fast twitch, glycolyic, white, jumping and weights energetics mitochondria glycolysis creatine kinase reaction adenylate kinase reaction fatigue exercise-induced changes in muscle structure clinical examples: hypocalcemic tetany, muscular dystrophy, malignant hyperthermy...
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- Spring '09