test _1 answers - spring 2009

test _1 answers - spring 2009 - Principles of Drug Action...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Principles of Drug Action (BIO 365) Test #1 Name:_____________________________ February 15, 2009 Each of the 16 multiple choice questions is worth 0.75 marks out of 30 (i.e., a total of 12/30) . 1. The sedative flunitrazepam has been given the street name “roofies” and is marketed by the drug company Roche under the name Rohypnol™. Which of the following statements about these drug names is TRUE ? A. Roofies is a non-proprietary name and Rohypnol is a proprietary name. B. Roofies is a proprietary name and Rohypnol is a common name. C. Roofies is a common name and Rohypnol is a non-proprietary name. D. Roofies is a non-proprietary name and Rohypnol is a common name. E. Roofies is a common name and Rohypnol is a proprietary name. 2. The chemical modification of the mold-derived antibiotic penicillin to create the new antibiotic oxacillin means that oxacillin is an example of a A. Pure compound. B. Galenical. C. Semi-synthetic compound. D. Synthetic compound. E. None of the above. 3. Which one of the following statements is TRUE ? A. A scopolamine patch for seasickness is an example of a percutaneous administration of a drug. B. Intrathecal injection are used to administer drugs for the purpose of a systemic effect. C. Drugs administered via suppository are subject to the first-pass effect. D. Drugs administered sublingually tend to be absorbed slowly. E. Drugs administered subcutaneously are quickly absorbed. 4. Aquaporins are A. A form of drug transport that involves ATP hydrolysis. B. Water-filled channels needed to allow drug molecules with high Pm/b values to cross cell membranes. C. Proteins that form pores between cells. D. Water-filled channels needed to allow drug molecules with low Pm/b values to cross cell membranes. E. Proteins found in blood that bind drug molecules, thus decreasing their rates of elimination. 5. Assume that the molecule ethane (CH3CH3) has a membrane/buffer partition coefficient of 100. If adding a hydroxyl group to an aliphatic molecule like ethane changes its membrane/buffer partition coefficient by a factor of 0.1, what will be the membrane partition coefficient of ethanol (CH3CH2OH)? A. 110 B. 90 C. 10 D. 100.1 E. 99.9 6. Which one of the following statements is FALSE ? A. Salicylic acid will be more rapidly absorbed at a pH of 9 than a pH of 2. B. Organic amines (bases) are more rapidly absorbed in the small intestine. C. Organic acids are more likely to be found in the uncharged form in the stomach than in the small intestine. D. The organic base morphine will be more rapidly absorbed at a pH of 10 than a pH of 5. E. Organic bases are more likely to be found in the charged form in the stomach than in the small intestine.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
7. If the GFR is 125 ml/min but a drug’s clearance via the kidney is 80 ml/min this means A. the drug must be filtered especially thoroughly. B.
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/08/2009 for the course BIO 51310 taught by Professor Sisson during the Spring '08 term at University of Texas.

Page1 / 6

test _1 answers - spring 2009 - Principles of Drug Action...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online