SAS lecture 12

SAS lecture 12 - 1800 Act of Union Celtic Angles, Saxons...

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Ireland Celtic Angles, Saxons Norsemen Catholic Protestant Part of England 1800 Act of Union Irish social system Land owners King of England Middlemen Farmers Laborers
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Eight pounds/day/person 2600 calories RDA Protein 128 % Vitamin C >100% Deficient: Calcium Vitamin D Vitamin B 12 1845 Plants collapsed Late blight of potato Introduced pathogen…. Phytophthora infestans
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Genetic uniformity Why was late blight so severe in 1845? High density of plants Cull piles From previous year Source of inoculum - all plants susceptible Cool, wet weather Produce spores Water Spores dispersal Water Infection Water Phytophthora infestans Water molds
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Over-crowded, unsanitary conditions Disease One million dead Starvation Disease
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Two million emigrated Mass migration to the new world Govt. responsibility for individual welfare Economic expansion of British Empire Social significance of the famine
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Scientific significance of the famine Germ Theory of Disease = Microbes cause disease Inoculation Control (not inoculated) no symptoms Reproduced symptoms Anton deBary 1861
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Robert Koch 1. Association of microbe with symptoms 2. Isolate microbe in pure culture 3. Inoculate to reproduce symptoms 4. Re-isolate microbe Thank you Koch’s postulates Anthrax 1890 Golden age of microbiology
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Genetic resistance Fungicides Crop rotation Prevention of late blight ~10,000 plant pathogenic fungi
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ENVIRONMENT HOST PATHOGEN DISEASE TRIANGLE COMPATIBLE PLANT-MICROBE INTERACTIONS ARE EXCEPTIONAL TOTAL PATHOGENIC SPECIES ~10,000 FUNGI 2000 NEMATODES 1200 VIRUSES 180 BACTERIA TOTAL DAMAGING ON TOMATO 12 FUNGI 2-3 NEMATODES 6 VIRUSES 4 BACTERIA Disease is the exception;
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SAS lecture 12 - 1800 Act of Union Celtic Angles, Saxons...

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