Lecture_19_Objectives

Lecture_19_Objectives - Lecture 19 Objectives At the...

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Lecture 19 Objectives At the completion of the lecture and the assigned reading, the student should be able to: 1.) Define the following terms [including what cell(s) the term applies to] immune evasion – mechanisms that pathogens have evolved over time to subvert immune detection and/or distruction primary immunodeficiency – inherited gene mutation compromises immune system secondary immunodeficiency – infection, disease, treatments (chemo, immunosuppressant), or suboptimal nutrition cause immunodeficiency 2) List the various strategies that pathogens have evolved to evade immune destruction, and which particular effector mechanism of the immune system this strategy subverts. Cont. variation of surface protein and/or carb Ags - lots of allele types (strep), change viral envelope protein, gene rearrangement Viral latency –latent in nerve cells or B cells, never know there Escaping phagocyte killing mech – prevents fusion of phagosome w/ lysosome and reps in phagosome, escape from phagosome b-4 fusion rep in cytosol,
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This note was uploaded on 03/22/2008 for the course MT 434 taught by Professor Hoag during the Fall '07 term at Michigan State University.

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Lecture_19_Objectives - Lecture 19 Objectives At the...

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