Glomerular%20Filtration.pdf - Glomerular Filtration NFP = GHP(CHP GOP Filtration coefficient Kf X NFP Kf normally is 12.5 mL\/mmHg Substance Water

Glomerular%20Filtration.pdf - Glomerular Filtration NFP =...

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Glomerular Filtration NFP = GHP (CHP + GOP) Filtration coefficient: K f X NFP K f normally is 12.5 mL/mmHg Substance Molecular Weight Filterability Water 18 1.000 Na 23 1.000 Glucose 180 1.000 Insulin 5,500 1.000 Myoglobin 17,000 0.75 Albumin 69,000 0.005 Filtration size = 8 nanometers (80 angstroms) Albumin size is 6 nanometers (60 angstroms) Very little is filtered because albumin is negatively charged. Factors that affect filtration rate: 1. Sympathetic nerves a. Reduce GFR by constriction of afferent and efferent arteriole b. Caused by severe hemorrhage, brain ischemia, severe stress
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  • Fall '14
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  • Glucose, Blood vessel, Glomerulus, afferent arteriole, efferent arteriole, Afferent arterioles

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