NR 283 Unit 1 ROK Cell.genetic.cancer.docx

NR 283 Unit 1 ROK Cell.genetic.cancer.docx

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Atlanta Campus Review of Knowledge Review of Knowledge (ROK) Course NR 283 Exam Exam 1 Purpose The Review of Knowledge (ROK) focuses on course outcomes, unit outcomes and key concepts to enhance student success on exams. Use this document as a focused guide for study in conjunction with assigned readings, PowerPoint presentations, and other course resources. Supplement this document by outlining your own notes from the textbook chapters and place your expanded more detailed notes in the Student Notes column. This document should NOT be used as a substitute for completing the assigned readings. Chapter 4 Cellular Alterations and Adaptation Key Concepts Chapters Student Notes Cell adaptation Cell alteration Cell necrosis Chapter 4 Atrophy -shrinkage of cell size Hypertrophy - increase in cell size –causes organ to enlarge. Dysplasia -abnormal Hyperplasia - increase in # of cells. Metaplasia - reversible replacement of on cell for another cell-these cells do not always act as the other cells. Cells will try to adapt to their environment. All forms of disease begin with cell injury. Cell death-necrosis-the sum of cellular changes after local cell death and the process of cellular autodigestion. Coagulative Necrosis -protein denaturation-kidneys, heart, POET - ROK Form Revised 5.3.16 1
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Atlanta Campus Review of Knowledge Aging Frailty Somatic death adrenal glands Liquefative Necrosis - caused by bacterial infection- Staph, Strep, and E.coli- Neurons and glial cells of the brain. Caseous Necrosis - Combo of coagulative and liquefactive necrosis- Turberculous- pulmonary infection-looks like cream cheese. Gangrenous Necrosis- Death of tissue from sever hypoxic injury Dry-Wet-Gas Atrophy, decreased function of cell, and loss of cells. Leads to Progressive stiffness and rigidity. Sarcopenia-loss of muscle tissue due to aging. Delicate and unbalanced- mobility, balance, muscle strength, motor activity, cognition, nutrition, endurance, falls, fractures and bone density. Death of the entire person- cessation of breathing, and circulation. 3 postmortem changes- Algor mortis-temp change. Livor mortis- skin color change. Rigor Mortis- Muscle stiffness and rigidity POET - ROK Form Revised 5.3.16 2
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Atlanta Campus Review of Knowledge 1. Cell adaption includes, atrophy , hypertrophy, and hyperplasia and metaplasia . 2. An example of atrophy is loss of muscle due to bedrest. 3. Hypertrophy is an example of excess growth of the thyroid caused by over stimulation by hormones. 4. When a muscle is used often and increases in size, it is considered an example of – hyperplasia . 5. Cell accumulation injury can consist of water, proteins , bilirubin, hemosiderin or fat. 6. When there is a lack of oxygen to the cell, ATP cannot be produced. 7. The lack of oxygen will cause the sodium-potassium pump to fail.
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