lecture 24 - BIO 311C March 21, 2008 Components of an...

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Unformatted text preview: BIO 311C March 21, 2008 Components of an Enzyme Catalyzed Reaction Reactant(s) Enzyme Product(s) Cofactor(s) Enzyme + Cofactor(s) + Reactant(s) Product(s) + Enzyme + Cofactor Can be written as: Not all enzyme-catalyzed reaction require a cofactor. * Some Unique Aspects of Enzymes as Catalysts 1. They are proteins.- All are globular.- Many are conjugated.- Some are monomeric, others are oligomeric. 2. Each one is very specific:- for the substrates it recognizes and acts on.- for the functional groups it modifies or moves.- for the kind of reaction it catalyzes. 3. They function in a rather narrow environmental range:- at a narrow temperature range.- at a narrow pH range. 4. Some are regulatory and are subject to sensitive control of their rate of catalysis. 5. Some are able to couple two reactions together. * Effect pH on an Enzyme acidic pH neutral or basic pH Shape of enzyme is altered by electrical repulsion between adjacent functional groups more negative charges enzyme enzyme * active site denatured active site Each enzyme is designed such that it functions optimally at the pH value of its normal environment....
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This note was uploaded on 03/23/2008 for the course BIO 311C taught by Professor Satasivian during the Spring '08 term at University of Texas at Austin.

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lecture 24 - BIO 311C March 21, 2008 Components of an...

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