Lecture17June1.pptx - DNA model London Science Museum...

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DNA model, London Science Museum
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Rosalind Franklin and Maurice Wilkins X-Ray crystallography Erwin Chargaff chemical analysis: equal amounts of the bases adenine (A) and thymine (T), and of Guanine (G) and cytosine (C) Genes composed of DNA: Phage group (USA) Linus Pauling (Caltech) and models Max Perutz: “The year 1953 became the annus mirabilis. The queen was crowned; Everest was climbed; DNA was solved; Huxley and the late Jean Hanson, then at MIT, discovered the sliding mechanism of muscular contraction; and I found a method of deciphering the X-ray diffraction patterns of crystalline proteins” “It has not escaped our notice that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material.”
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Physics of Life vs Physics of Death A. V. Hill, 1944: “The Need for an Institute of Biophysics”: training and promote
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