ch 6.docx - THE IMMUNE SYSTEM FOURTH EDITION CHAPTER 6...

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THE IMMUNE SYSTEM, FOURTH EDITION CHAPTER 6 Which of the following cell-surface markers differentiates hematopoietic stem cells from other cell constituents in the bone marrow? a. pre-B-cell receptor b. BAFF receptor c. CD34 d. CD4 e. membrane-bound stem-cell factor (SCF). Which of the following is characteristic of a large pre-B cell? a. VDJ is successfully rearranged and μ heavy chain is made. b. V–J is rearranging at the light-chain locus. c. μ heavy chain and λ or κ light chain is made. d. V is rearranging to DJ at the heavy-chain locus. e. D–J is rearranging at the heavy-chain locus. Which of the following statements is correct? a. The κ light-chain genes rearrange before the heavy-chain genes. b. The κ light-chain genes rearrange before the λ light-chain genes. c. The λ light-chain genes rearrange before the heavy-chain genes. d. The λ light-chain genes rearrange before the κ light-chain genes. e. The μ heavy-chain genes rearrange first and then the λ light-chain genes rearrange. Immature B cells develop into B cells in the a. subendosteum b. bone marrow c. thymus
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d. blood e. secondary lymphoid organs. Place the following phases of a B cell’s life history in the correct chronological order. a. negative selection b. attacking infection c. finding infection d. searching for infection e. repertoire assembly f. positive selection. e-- a - f - d - c - b Place the following stages of B-cell development in the correct chronological order.
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  • Winter '17
  • GREGORYWEIGEL
  • B cell, B-cell development, light-chain genes

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