cardiac1 - Lecture Outline March 7, 2008 Cardiovascular...

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Lecture Outline March 7, 2008 Cardiovascular System I Anatomy of heart Layers of the heart wall epicardium myocardium endocardium (endothelium) Blood flow     Two circuits: 1. pulmonary 2. systemic      Heart Valves:         atrioventricular valves: tricuspid (R), bicuspid (L)     Coronary circulation Biology 141: Physiology 1
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Lecture Outline Cardiac muscle and the conduction system Cardiac muscle cells Cardiac muscle AP phase 0: Na +  channels open phase 1: Na +  channels close; fast K +  channels open -- early  partial repolarization  phase 2: plateau phase--, K +  channels close; Ca 2+  channels open phase 3: Ca 2+  channels close; slow K +  channels open phase 4: resting potential Effective refractory period  (ERP) limits the frequency of action potentials (and therefore contractions) that can be  generated  by the heart Biology 141: Physiology 2
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cardiac1 - Lecture Outline March 7, 2008 Cardiovascular...

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