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Unformatted text preview: independent of nerves or hormones primary function is to regulate the local blood flow 1. myogenic mechanisms 2. endothelial factors 3. paracrines 4. metabolic by-products or hypoxia 5. heat, cold Extrinsic factors originate from outside of the organ or tissue in which the blood vessel is located primary function is to regulate arterial blood pressure by altering systemic vascular resistance a. neural 1 and 2 adrenergic receptors b. hormonal angiotensin II and ADH (vasopressin) vasoconstriction ANF vasodilation E 2 adrenergic receptors Pathologies Atherosclerosis stenosis thrombus (thrombi) Coronary artery disease (CAD) ischemia hypoxia, anoxia infarction Peripheral Arterial Disease (PAD) claudication Strokes embolism Biology 141:Physiology Lecture Outline Aneuryism Biology 141:Physiology...
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- Spring '08