epil_0011.docx - with the status epilepticus Several...

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with the status epilepticus. Several genetic models have been discovered for absence epilepsy. Although this type of epilepsy is generally thought to have a genetic component, and these animal models provide a basis for exploring the molecular mechanisms of absence epilepsy, it is not clear that every mutation that leads to absence epilepsy in an animal is relevant to the human condition. Collectively, these models have provided fundamental information about the molecular and cellular events transpiring in cortical neurons and their circuits during interictal discharges and during the transition from the interictal discharge to a fully developed seizure. Initiation and spread of seizures A number of terms are widely used in describing the results of epilepsy research and so should be defined. The epileptogenic focus is a cortical area containing abnormally functioning neurons which is determined electroencephalographically during the interictal period; thus, it is an electrophysiological concept (Figure 1, B). The epileptogenic zone
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  • Fall '15
  • Seizure, Cortical Neurons, Epileptic seizures, Absence Epilepsy, abnormally functioning neurons

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Christopher Reinemann
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