epil_0019.docx - THE HISTORY OF EPILEPSY 1 Also in the 19th...

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THE HISTORY OF EPILEPSY 1 Also in the 19th century, with the development of the concept of functional localization in the brain (13) and the discovery, for example, of the motor cortex (14), the concept of “epileptiform” or “partial” seizures arose as models for the study of “generalized” seizures (15, 16). By meticulously studying the clinical features of unilateral epileptiform motor seizures, Jackson was able to conclude, as was later confirmed experimentally, that the motor cortex was concerned with movements rather than individual muscles (16). Paroxysmal episodes of an intellectual, emotional or behavioural kind, including hysteria or “hystero-epilepsy” (17), were more difficult to classify and localize; it was not until the discovery of human electroencephalography (EEG) in the 20th century (18) that the concepts of temporal lobe or frontal epilepsy were gradually clarified, and psychological concepts of hysteria evolved. Electrical basis of epilepsy As the concept of a brain disorder
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