NURS 6501N-14: Advanced Pathophysiology Week 7: Hematological System INITIAL POST Anemia Anemia develops when there is a reduction, or the blood lacks enough healthy erythrocytes or hemoglobin (Huether & McCance, 2017, p. 513). Hemoglobin is the central part of red blood cells that binds to oxygen. A reduced or abnormal red blood cells, or hemoglobin means a reduction in the oxygen-carrying capacity of the body. Therefore, the cells of the body will not get enough oxygen, and that results in fatigue or dizziness due to tissue hypoxia. Anemia is the most common blood condition in the U.S., and it affects about 5.6% of the people in the U.S. (Harigae & Furuyama, 2010). Women, young children, and people with chronic diseases are at increased risk of anemia. Iron-deficiency anemia is the most common type of anemia and occurs when the body does not have enough iron. The body needs iron to produce hemoglobin. Iron-deficiency anemia results from excessive loss or inadequate intake of iron-rich foods. Decreased serum iron characterizes Iron-deficiency anemia, also reduced serum ferritin and reduced percentage transferrin saturation with an increase in total iron binding capacity (TIBC) is noted (Fujiwara & Harigae, 2013). Iron-deficiency anemia occurs mostly in the elderly, infants, females and pregnant women. Pathophysiology of Sideroblastic Anemia Sideroblastic anemia (SA) and iron-deficiency anemia are microcytic-hypochromic anemias meaning that the erythrocytes formed are abnormally small and contain abnormally reduced amounts of hemoglobin (Huether & McCance, 2017, p. 517). Sideroblastic anemia is
characterized by anemia in which the bone marrow produces ring sideroblasts rather than healthy erythrocytes. Ring sideroblasts are erythroblasts characterized by iron accumulation in perinuclear mitochondria due to impaired iron utilization. In sideroblastic anemia, the body has available iron but cannot incorporate it into hemoglobin, which is required by erythrocytes to transport oxygen efficiently.
You've reached the end of your free preview.
Want to read all 6 pages?
- Fall '17
- keisha lovence
- sideroblastic anemia