Muscle Growth Essay

Muscle Growth Essay - Muscle Growth Essay Myoblasts are the...

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Muscle Growth Essay Myoblasts  are the early progenitor cells of muscles, arising from the embryonic mesoderm that has  been organized in somites. Pluripotent cells in the somites come under the function of patterning factors —that arise  from specific locations and establish concentration gradients as a result of diffusion The way these protein control differential gene expression leading to certain precursor cells  becoming determined  to eventual differentiated lineages Initial production of these factors is not simultaneous Some factors exert position feedback by provoking their own synthesis in na ï ve Gives rise to progressive movement of production sites—often in a cranio-caudal direction Wnt1-  Arises from dorsal regions of neural tube and surface ectoderm. Directs formation of  dermomyotome —that eventually produces myoblasts Shh--     From ventral part of neural tube Signals somite cells to become precursors of bone and cartilage Pax3— From dorsal regions Triggers expression of  myoD  gene—the “master regulator” for muscle lineages
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