07_BMB462_EXAM1_FormA_Key

07_BMB462_EXAM1_FormA_Key - BMB 462-EXAM I Spring 2007 Name...

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BMB 462—EXAM I Spring 2007 FORM: A Name_______________________________ Student #: __________________________ This exam is 100 points total. There are 5 problems (indicated) worth 2.5 points each. The remaining 25 questions are worth 3.5 points each. Select the ONE BEST answer for each question. H C O O CH 2 O O CH 2 O O C C C HO C CH CH (CH 2 ) 12 CH 3 CH H N O O CH 2 OH OH OH OH H C O C H C O O CH 2 O O C CH 2 O O P O - O CH 2 CH 2 (CH 3 ) 3 N + C H C O O CH 2 O O C CH 2 O O P O - C OH OH O P O O - - O O P O O - - O OH H O 1 2 3 4 Questions 1-5 refer to the 4 molecules drawn above. 1. (2.5 pts.) Which of the above molecules is a non - membrane lipid? A. Molecule 1 B. @Molecule 2 C. Molecule 3 D. Molecule 4 E. Molecules 1 and 2 2. (2.5 pts.) Which of the above molecules is a sphingolipid? A. @Molecule 1 B. Molecule 2 C. Molecule 3 D. Molecule 4 E. Molecules 1 and 4 1
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3. (2.5 pts.) Which of the above molecules has a fatty acid that becomes the precursor of the eicosanoid hormones (the prostaglandins, thromboxanes, and leukotrienes) when it is cleaved off? A. Molecule 1 B. Molecule 2 C. Molecule 3 D. @Molecule 4 4. (2.5 pts.) What is the enzyme that removes the fatty acid, from the appropriate molecule shown above, that becomes the precursor of eicosanoids? A. Phospholipase A 1 B. @Phospholipase A 2 C. Phospholipase C D. Phospholipase D E. Hormone-sensitive lipase 5. (2.5 pts.) What would be the correct order of elution of the above 4 molecules from an adsorption chromatography column—listed from first to elute to the last to elute from the column? A. Molecule 1, Molecule 2, Molecule 3, Molecule 4 B. Molecule 2, Molecule 1, Molecule 3, Molecule 4 C. Molecule 3, Molecule 4, Molecule 1, Molecule 2 D. @Molecule 2, Molecule 1, Molecule 4, Molecule 3 E. Molecule 1, Molecule 2, Molecule 4, Molecule 3 6. The process of digestion and absorption of dietary lipids requires all of the following EXCEPT : A. Emulsification of large lipid droplets by bile salts. B. Formation of mixed micelles, which are small enough to be absorbed by intestinal mucosal of cells. C. @Activation of hormone-sensitive lipase to degrade triacylglycerols (TAGs). D. Co-lipase 7. Which of the following are general features of signal transduction? A. Integration B. Specificity C. Desensitization D. Amplification E. @All of the above 2
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8. Which of the following statements about lipoprotein particles is CORRECT ? A. @LDL lipoprotein particles contain the apoprotein B-100, which is the ligand for cellular LDL receptors. B. HDL lipoprotein particles contain primarily triacylglycerols (TAGs). C. The lipoprotein particles arranged by size from smallest to largest is: chylomicrons, VLDL, IDL, LDL, and HDL.
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07_BMB462_EXAM1_FormA_Key - BMB 462-EXAM I Spring 2007 Name...

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