REVIEW_QUESTIONS-LABS1-6

REVIEW_QUESTIONS-LABS1-6 - EXERCISE 1 The Theory of...

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EXERCISE 1- The Theory of Evolution-Population Genetics Define (and understand) natural selection What is the difference between an allele, phenotype and genotype? What is the difference between a dominant allele? Recessive allele? What is adaptation? Adaptation over time can lead to what? (p.2) How does the book define a population? (p.2) Define gene pool. What are two common causes of changes in allele frequencies between  generations? (p.2) Is natural selection or genetic drift considered an adaptive change? (p.2)  List the five assumptions of the Hardy-Weinberg model.  Write the Hardy-Weinberg equation.   Be able to solve Hardy-Weinberg  problems. p 2 =used for calculating the frequency of what? 2pq=used for calculating the frequency of what? q 2 =used for calculating the frequency of what? What   is   meant   when   we   say   that   a   population   is   at   Hardy-Weinberg  equilibrium? Write the equation for calculating   allele   frequencies. Be able to solve a  problem.  When we tasted PTC paper in class (see page 5), the percentage of those  who are tasters are represented by the equation p 2 +2pq, why? Why are non- tasters represented by q 2 ? Make sure that you understand the experiment where we ran the gels.  (electrophoresis) What did the bands represent? Why were we looking at those bands? What  does this experiment have to do with malaria and sickle cell anemia? Malaria and the Sickle Cell Mutation.  What causes malaria? What is the cause of sickle cell anemia?
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What is heterozygote advantage? What is recessive refuge? What is a recessive deleterious allele? What is the relationship between  malaria and sickle cell anemia? When considering a sickle cell allele and a normal hemoglobin allele, which  genotype offers resistance to malaria? How is a recessive deleterious allele allowed to remain in a population  (assuming that the homozygous recessive genotype causes death)? If a town is ravaged by malaria, would you expect the frequency of the  sickle cell allele to increase or decrease? How are the malaria death rate and the sickle cell death rate related? As frequency of the sickle cell allele increases, what happens to the number  of actual malaria deaths? Sickle cell deaths? As the frequency of the sickle cell allele HbS increases, what happens to the  frequency of the HbA (normal hemoglobin allele).? If   the   malaria   death   rate=0,   what   would   you   expect   to   happen   to   the  frequency of the sickle cell allele? Hemoglobin allele? Number of malaria  deaths? Number of sickle cell deaths? Ask yourself the same questions as above, except imagine the malaria death 
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This note was uploaded on 03/26/2008 for the course BIOL 112 taught by Professor Vaughn during the Spring '08 term at Texas A&M.

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REVIEW_QUESTIONS-LABS1-6 - EXERCISE 1 The Theory of...

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