MD 5 Discussion 1 Article B - Journal Article Critique Injury Disasters and Hazards The coast of northwestern Spain was heavily contaminated in

MD 5 Discussion 1 Article B - Journal Article Critique...

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Journal Article Critique: Injury, Disasters, and Hazards The coast of northwestern Spain was heavily contaminated in 2002 when an oil tanker Prestige spilled more than 67,000 tons of bunker oil. The authors performed a cross-sectional study to assess respiratory effects and chromosomal damage in workers who were involved in the clean-up of the oil spill 2 years after the exposure. The participants enrolled in the study were local fishermen highly exposed or not exposed to the oil two years after the spill. The exposed group had 501 and the not exposed group had 177. They collected data on respiratory symptoms, forced spirometry, methacholine challenge, markers of oxidative stress (8-isoprostane), airway inflammation (interleukins, tumor necrosis factor-α, and interferon-γ), and growth factor activity in exhaled breath condensate; and chromosomal lesions and structural alterations in circulating lymphocytes. They found that those exposed to oil were at increased risk for lower respiratory tract symptoms compared to those not exposed.

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