Genetics-Fall07(11-1-2007) - Gene regulation: Turning...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Gene regulation: Turning transcription on and off specifically cell differentiation turning genes on and off happens specifically, in response to environmental stimuli (lac operon), w/ respect to DNA that encodes the gene needs to extent beyond the bases that encode the protein (translational start codon- AUG-), transcriptional start site (almost never the same as the translational start site) (is always 5’ of or upstream of the translational start site), translational and transcriptional stop sites example a point mutation between the transcription and translational start site MIGHT alter the protein (alter the message stability, how its transported around the cell) but wont alter the sequence per say of the protein open reading frame encodes proteins mRNA that codes is also a part of the gene Ex. mutations in DNA at point of mRNA 3’ creation could lead to protein mutation elements of DNA where the proteins bind that actually regulate transcription (RNA polyermase binding to lac promoter) binding of transcription factors (promoters?) the main point of Tuesdays lecture is that the “gene” includes more than just the region that encodes for the protein!!! Turn gene on and off
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/26/2008 for the course BIOL 202 taught by Professor Kieber-hogan during the Fall '08 term at UNC.

Page1 / 3

Genetics-Fall07(11-1-2007) - Gene regulation: Turning...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online