Genetics-Fall07(9-27-2007) - *unordered tetrads in budding...

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**unordered tetrads in budding yeast ** AB x ab What are three tetrads we can get from this? PD: AB AB ab ab Whats the most frequent even in meiosis? No crossovers at all So, the progeny with biggest number in F1 = the parental genotype NPD: Ab Ab aB aB 2 diff genotypes that aren’t the same as the parents If there is no linkage, the ratios tell us…PD = NPD If there is linkage, the ratios tell us… NPD < < PD ?if there is no NPD, there is…what? TT: AB Ab aB ab one of each 4 genotypes, non like parents (so ur possibilities are PD, NPD, and TT) **using tetrads to find MAP distances ** (I think) Double crossovers: (when doing MAP distances, u need to know something about single vs. double crossovers… I think Types of double crossovers: 1 that is 2 strand \ 2 that are 3 strand -- = total types of double crossovers = 4 1 that is 4 strand / Use the # of NPDs = double crossovers (bc the 4 types of double crossovers should occur with equal frequency so total # double crossovers is NPDs x 4)
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This note was uploaded on 03/26/2008 for the course BIOL 202 taught by Professor Kieber-hogan during the Fall '08 term at UNC.

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Genetics-Fall07(9-27-2007) - *unordered tetrads in budding...

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