Lecture 13 (Skafar 1).pdf - Female Reproductive Physiology...

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Female Reproductive Physiology Debra F. Skafar Boron and Boulpaep Ganong
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1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y Human chromosomes
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The early gonad and germ cell migration (52-3)
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Transformation of the genital ducts (52-4)
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Puberty
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Adrenal Androgen Levels in Serum During Puberty Girls Boys Age (yrs) 7 9 11 15 13 Adult 1 2 4 3 5 6 Serum DHEA (ng/ml)
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Gonadotropin function during life (54-2)
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Structure of kisspeptin Tena-Senpere, 2006
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Regulation of the hypothalamic/pituitary/ gonadal axis by leptin and kisspeptin Tena-Sempere, 2006
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FSH, LH Estradiol and Sex Steroid Binding Globulin (SSBG) during Puberty in Girls Serum FSH or LH ( μ g/100ml) or Estradiol (ng/100ml) SSBG (nmole/l) SSBG FSH Estradiol LH
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GH Secretion During Puberty Marshall - Tanner Stages GH Secretion Rate (U/24 hrs) Basal GH (mU/l) Boys Girls
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Serum IGF I During Puberty Girls Boys Adults Serum IGF I (U/ml) 4 3 2 1 0 I II III V IV
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Females Numbers indicate stage of development 8 9 10 11 12 13 14 15 16 9½-14½ 10-15½ Bud 8-13 14½ -18 10-15 14-18 2 3 4 5 Height spurt menarche Breast Pubic hair Age (yrs) 2 3 4 5 Sequence of secondary sexual development in females. The range of age is indicated.
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Adult Female Reproductive System
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Hormones of the female reproductive system GnRH (hypothalamus) LH, FSH (pituitary) Estrogen and progestins (ovary) Inhibin (ovary)
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Functions of the ovaries • Gametogenic • endocrine
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  • Winter '18
  • podolsky
  • progesterone, adult female, LBD

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