Britney Pettigrew_DB1_WK3_PharmacotherapyCardiovascular.docx

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Britney Pettigrew Pharmacotherapy for Cardiovascular Disorders Week 3 DB: Initial Post Case Study A.O. is a patient who has a history of obesity with a recent nine pound gain. A.O. also has a history of hypertension and hyperlipidemia. Drugs the patient is currently taking are atenolol 12.5 mg daily, doxazosin 8 mg daily, hydralazine 10 mg four times daily, sertraline 25 mg daily, simvastatin 80 mg daily. For this case study, I am to reflect on one factor for this patient that may influence the pharmacokinetics and pharmacodynamics that would possibly affect the recommended drug therapy for this patient. I am to us the knowledge learned in this course to determine if the patient's drug treatment should be changed or an alternative treatment should be prescribed. Prescription Medications The patient is taking several medications concurrently. A.O. is taking a beta-adrenergic blocker (atenolol), a peripheral alpha-1 receptor blocker (doxazosin), a direct vasodilator (hydralazine), an SSRI (sertraline), and a statin (simvastatin). When assessing this case study, several things come to mind: how old is this patient? What type of hypertension are we dealing with? Is this essential hypertension, primary, secondary, or resistant hypertension? How high have the blood pressures been? Is this patient compliant with the medication regimen? Is this patient a male or female? What race is the patient? Regardless of the answer to some of these questions, hydralazine is a direct vasodilator that should only be used in severe or essential hypertensive situations (Archangelo et al., 2017).
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  • Fall '13
  • Week 3 Discussion, Resistant hypertension, Archangelo et al.

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