1.Chromosome_Study_Guide_xx.ppt - Unit 1.Chromosome This is your course study guide Please save it for yourself and type your notes in the note sections

1.Chromosome_Study_Guide_xx.ppt - Unit 1.Chromosome This is...

This preview shows page 1 - 13 out of 104 pages.

Unit 1.Chromosome This is your course study guide. Please save it for yourself and type your notes in the note sections.
Image of page 1

Subscribe to view the full document.

Readings This study guide Those link-outs in this study guide Chromosome Struture: Ch 5 p.179-184 Mitosis: Ch. 18 p. 622-633 Meiosis: Ch. 19 p. 648-657 Pedigrees: Griffiths
Image of page 2
Part 1: The Chromosome Theory of Inheritance
Image of page 3

Subscribe to view the full document.

Concepts for Study Observations and experiments that placed the hereditary material in the nucleus on the chromosomes Mitosis as a mechanism for ensuring cells in the organism carry the same set of chromosomes Meiosis as a mechanism for distributing one set of chromosomes to gamete cells Pedigree analylsis for traits mapped to chromosomes Validation of the chromosome theory of inheritance Y chromosome and mitochondrial DNA mapping Ethics surrounding chromosome technologies
Image of page 4
Evidence that Genes Reside in the Nucleus Since the 1800’ s, fertilization mechanisms have been understood from a microscopy level Frog and sea urchin fertilization was recorded in a time-lapse manner Began to clarify the notion that hereditary material was in the nucleus
Image of page 5

Subscribe to view the full document.

Evidence that Genes Reside in Chromosomes 1880s: innovations in microscopy and staining techniques identified thread-like structures later called chromosomes 1920s-1940s: Chromosomes carry the genetic material, and they were shown to be composed of protein and nucleic acid 1940’ s: DNA is the Genetic material (Avery, McCleod, McCarty following Griffiths work)
Image of page 6
Image of page 7

Subscribe to view the full document.

Sex Chromosomes Henking (Germ), 1891 hypothesized the “ X element McClung (KS), 1901 (student= Sutton) hypothesized the X element involved in sex determination Sutton, 1903 determined grasshopper sperm represented 2 classes of gametes
Image of page 8
Sex chromosome idea extends to humans Provide basis for sex determination One *sex has matching pair Other *sex has one of each type of chromosome Photomicrograph of human X and Y chromosome If DNA is thin, why are these so thick? *”sex” to be defined next slides
Image of page 9

Subscribe to view the full document.

*Sex determination in humans Children receive only an X chromosome from XX parent and either an X or Y from XY parent XY parent gives either X or Y in sperm XX parent can only give an X type of egg 50 % 50 % Progeny 50% XX and 50% XY
Image of page 10
Orientation as a spectrum HUMANS ARE COMPLICATED The latest science in genetics backs up ideas of Variation in physical sex Variation in gender identity Variation in sexual orientation Variation in genes involved in development of sex Some resources: 112317.htm
Image of page 11

Subscribe to view the full document.

“Biological Sex” –vs- Gender In human sexual reproduction discussions, folks typically talk about the "female” or “mother” as the provider of the egg and the “male” or ”father” as the provider of the sperm Note: The scientific literature refers to this as “biological sex,” but the term does not make assumptions about gender We are learning more and more about the concept of gender from the science of genetics and neuroscience, but also from social sciences.
Image of page 12
Image of page 13

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern

Ask Expert Tutors You can ask 0 bonus questions You can ask 0 questions (0 expire soon) You can ask 0 questions (will expire )
Answers in as fast as 15 minutes