NURS6501.WEEK5.DISCUSSION2.docx - Week 5 Discussion 2 Anaphylactic Shock Anaphylactic shock begins with exposure of a sensitized individual to an

NURS6501.WEEK5.DISCUSSION2.docx - Week 5 Discussion 2...

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Week 5 Discussion 2 Anaphylactic Shock Anaphylactic shock begins with exposure of a sensitized individual to an allergen and it results from a widespread hypersensitivity reaction known as anaphylaxis. The lifetime prevalence of anaphylaxis is 0.5% to 2% (Huether & McCance, 2017). Some of common allergens that are known to cause reactions are venoms, shellfish, peanuts, latex, and some medications (Huether & McCance, 2017). For the sake of the given scenario, I will identify the multisystem physiologic progression that occurs in anaphylactic shock. I will then discuss when it is a good idea to refer patients to emergency care versus treating, as an outpatient and lastly, I will discuss how patient factors like genetics and age might impact the process of anaphylactic shock. Multisystem Physiologic Progression The multisystem physiologic progression begins when a sensitized individual is exposed to an allergen. When this happens, the allergens initiate a vigorous humoral immune response that results in the production of large quantities of immunoglobulin E antibody (IgE) (Huether & McCance, 2017). Allergens bound to IgE causes degranulation of mast cells, which then release a large number of vasoactive and inflammatory cytokines (Huether & McCance, 2017). According to Hammer & McPhee (2014), during an episode of anaphylactic shock the body releases large amounts of histamine causing vasodilation; the blood pressure then falls because the size of the vascular system exceeds the amount of blood in it even though blood volume is normal. The primary symptoms of this type of shock includes anxiety,
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