NURS6521Week1Diss.docx - NURS 6521 Week 1 Discussion...

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NURS 6521 Week 1 Discussion Pharmacokinetics and pharmacodynamics are important factors in the plan of care for any patient population. When taking care of elderly patients and prescribing medications, it is important for healthcare prescribers to know how medications will affect elderly patients. One example of the importance of pharmacokinetics and pharmacodynamics playing a factor in patient care was during the treatment of a 75-year-old white female. She was forgetful and lived alone will little outside help for daily task and healthcare. This patient used acetaminophen (Tylenol) for pain on a regular basis to treat her arthritis and generalized pain. During a detailed history, she reported that she was careful not to exceed the recommended daily dose of acetaminophen. Additional medications taken by this patient included digoxin for an apparent cardiac condition. The patient presented with nausea, vomiting and abdominal pain that was sudden in onset. Acetaminophen, a safe and effective pain reliever, is one of the most popular OTC pain relivers in the U.S. Elevated LFTs and renal function labs provided clues to the healthcare provider that drug toxicity may be present. Pharmacokinetics is defined as the study of the time course of drug absorption, distribution, metabolism, and excretion (Spruill et al., 2014). Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient (Spruill et al., 2014). Pharmacodynamics refers to the relationship between drug concentration at
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  • Fall '13
  • Pharmacology, digoxin, elderly patients, Elderly individuals, CLINICAL PHARMACOKINETICS

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