195347257-Nicotine-and-Health.pdf - NICOTINE HEALTH NICOTINE and HEALTH A publication of the WRITTEN BY Dr. Murray Laugesen public health medicine

NICOTINEandHEALTHWRITTEN BYDr. Murray Laugesenpublic health medicine specialistQSO, MBChB, FNZCPHM, FRCS (Edin)A publication of the

American Council on Science and Health1995 Broadway, Suite 202New York, New York 10023-5860Tel. (212) 362-7044 • Fax (212) 362-4919URL: • Email: [email protected]Publisher Name: American Council on Science and HealthTitle: Nicotine and HealthPrice: $12.95Author: Dr. Murray LaugesenSubject (general): Science and HealthPublication Year: 2013 Binding Type (i.e. perfect (soft) or hardcover): PerfectISBN: 978-0-9727094-6-0NICOTINE AND HEALTH.Copyright © 2013 by American Councilon Science and Health. All rights reserved. No part of this book may beused or reproduced in any matter whatsoever without written permis-sion except in the case of brief quotations embodied in critical articlesand reviews. For more information, contact:

Acknowledgements.The paper relies on the work of numerous researchers in many fields, andthese are referenced. A number of distinguished reviewers gave excellent comments and are grate-fully acknowledged.Conflict of interest.None declared. The author has carried out research for the World HealthOrganization, the New Zealand Ministry of Health and other government agencies, several electroniccigarette companies and many non-government organisations.Author information. Dr. Murray Laugesen is a public health physician. He was principal medicalofficer in the New Zealand Ministry of Health from 1984-1995 for the passage of major tobacco con-trol legislation. In 1998 he was awarded the World Health Organization Tobacco or Health medal,the citation reading “for achievements deemed worthy of international recognition in promoting theconcept of tobacco-free societies.” In 2000 he was awarded the Queen’s Service Order for public ser-vices. Dr. Laugesen has authored over 40 papers on a wide range of tobacco control issues, and since2000 he has been involved in researching various tobacco and nicotine products as alternatives tocigarettes. He operates two websites, his consulting company at and a tobaccopolicy think tank charitable trust, at Clive BatesPublic interest consulting and ana-lytical advocacyLondon, United KingdomJosh Bloom, Ph.D.Director of Chemical andPharmaceutical SciencesAmerican Council on Science andHealthJoseph R. DiFranza, M.D.Professor, University ofMassachusetts Medical SchoolWorcester, MAKarl Fagerström, Ph.D.President, Fagerstrom ConsultingABVaxholm, SwedenBrad Rodu, D.D.S.Professor of MedicineEndowed Chair, Tobacco HarmReduction ResearchUniversity of LouisvilleGilbert Ross, M.D.Executive/Medical DirectorAmerican Council on Science andHealthElizabeth M. Whelan, Sc.D.,M.P.H.PresidentAmerican Council on Science andHealthTHE AMERICAN COUNCIL ON SCIENCE AND HEALTH APPRECIATESTHE CONTRIBUTIONS OF THE FOLLOWING INDIVIDUALS WHOREVIEWED THIS REPORT

Nicotine and Health4Summary......................................................................................................8Introduction................................................................................................10Glossary.......................................................................................................10Nicotine: Physical and pharmacological properties.....................................13Nicotine—an acute poison.................................................................................13