Week 01 - Escherichia Coli

Week 01 - Escherichia Coli - elephant. Jacques Monod. is...

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1 Microbe of the Week #1 Escherichia coli E. coli is a common inhabitant of the digestive system of warm-blooded animals. • We know more about the biology of than any other organism. • Some strains can cause serious diseases of humans and animals. Microcolony of Produced from a single cell in 11.5 hrs at 37 C. is a gram negative, rod- shaped bacterium cell disrupted to release DNA. A cell 2-3 μm long contains 1.2 mm of DNA. Flagella (above) and fimbriae (below) surround the cells. A typical cell is 1 X 3 μm. A common inhabitant of our intestines. .. • Each gram of feces contains 10 8 - 10 9 E. coli cells. and other microflora of the gut provide vitamins (K and B-complex). • Gut microflora protects against opportunistic pathogens. False color scanning electron micrograph of E. coli cells. "Once we understand the biology of Escherichia coli , we will understand the biology of an
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Unformatted text preview: elephant. Jacques Monod. is the most intensively studied organism on the planet. An important model system in microbiology, biochemistry, genetics, etc. An indispensable tool in genetic engineering. Complete DNA genome sequence published in 1997. Program is underway to catalog all the proteins that it produces ( proteome project). Some strains of cause serious disease. .. Pathogenic strains produce toxic chemicals that allow them to infect the host. Some strains cause tremendous child mortality in developing world. Strain 0157 is a foodborne pathogen that can cause serious intestinal and kidney disease. Electron micrograph of 0157:H7...
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