13 - • Termination o 1. Stop code causes binding of...

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Protein Synthesis: Initiation o 1. M-RNA attaches to small subunit o 2. Exposed AUG > t-RNA with amino acid o 3. Large subunit attaches UUU phenoalenine Nucleotide: A, U, G, C Sickle cell anemia: one different o Pleiotrope: one gene affects a lot of traits Protein Synthesis o Messenger RNA Formed along one side of DNA Ribose different sugar RNA has uracil for thymine RNA single stranded Ribosomal RNA o Makes up ribosomes o “Reads” message and attaches appropriate amino acid to growing chain Elongation : occurs in the cytoplasm o 1. 2 nd t-RNA arrives o 2. Peptide bond forms between amino acids o 3. Empty t-RNA leaves, other moves over Ribosomes on the ER tend to make proteins for outside the cell
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Unformatted text preview: • Termination o 1. Stop code causes binding of releasing factor o 2. Polypeptide is released o 3. Ribosomal subunits separate from message • Protein Synthesis Review o 1. DNA splits o 2. m-RNA formed transcription o 3. m-RNA to cytoplasm o 4. m-RNA read by ribosome Initiation, elongation, termination o 5. t-RNA brings in appropriate amino acid called for by code o 6. Amino acid is added to chain • Mutations o Changes in DNA result in Mutations o Deletion or Insertion: serious Messes up everything downstream o Substitutions: one gene replaced for another Only messes up one amino acid • Inability to breakdown phenoalynine causes PKU...
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This note was uploaded on 03/26/2008 for the course BIOL 101 taught by Professor Hogan during the Spring '08 term at UNC.

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13 - • Termination o 1. Stop code causes binding of...

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