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Describe the levels of evidence and provide an example of the type of practice change that could result from each.A cornerstone of EBM is the hierarchical system of classifying evidence. This hierarchy is known as the levels of evidence. Practicing evidence-based medicine encourages clinicians to integrate valid and useful evidence with clinical expertise and each patient's unique features, enabling clinicians to apply evidence to the treatment of patients.There are five main steps to practicing evidence-based medicine: -Identify knowledge gaps and formulate a clear clinical question.Search the literature to identify relevant articles.Critically appraise the articles for quality and the usefulness of results; always question whether the available evidence is valid, important and applicable to the individual patient.Implement clinically useful findings into practice.Evaluate performance using audit.Hierarchical systems for levels of evidence used in recommendations and guidelines.A variety of grading systems for evidence and recommendations is currently in use. The system used is usually defined at the beginning of any guidelines publication.