SPPH 381C Oct 1.docx - Biological Mechanisms Epigenetics...

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Biological Mechanisms: Epigenetics & the Life Course Approach to Health Oct. 1, 2018 What’s the point of GIS in environmental health studies? What can it be used for? Spatial health outcome clusters Does exposure level correspond to disease (health) prevalence? Spatial patterns of exposures Exposure—outcome—confounding? Stress Used in many different ways E.g. exposure to a stressor, the bodily stress response etc. What is biological stress An adaptive response of an organism to external or internal threats—the general adaptive syndrome Stress concepts: Homeostasis : maintenance of stable bodily conditions throughout varying environmental conditions Allostasis : achieving homeostasis through change in behaviour (*through change we keep the balance) “an active process by which living organisms adapt to potential threats to their survival and changes in their environment (often referred to as ‘stressors’) in order to maintain
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