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MAIN QUESTION POSTPathophysiology of Iron Deficiency AnemiaIron deficiency is one of the most prevalent causes of anemia (Miller, 2013). Typically, there are two possible causes of iron deficiency anemia, which are related to dietary intake or chronic blood loss (Camaschella, 2015). Certain metabolic disorders may also cause iron deficiency anemia (Camaschella, 2015). Iron is needed in the body for essential functions including “respiration, energy production, DNA synthesis, and cell proliferation” (Camaschella, 2015, para. 2). Iron is needed for hemoglobin and heme production (Miller, 2013). Iron can be recycled. Therefore, the body is able to keep enough for hemoglobin production and to keep a store of iron (Huether & McCance, 2017). When there is an issue that causes a decrease in the amount of iron available, iron is depleted faster than it can be restored (Camaschella, 2015). Thiscreates an insufficient amount of iron being distributed to the bone marrow, thus leading to the production of iron-deficient red blood cells (Miller, 2013).
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Hemoglobin, Iron deficiency anemia, Huether, Sideroblastic Anemias